Jessse was a Man-Snake that appeared in the episode Summer Semester. Jessse and Thark wanted to have a battle of the bands to decide what race would rule the world (Man-Snake or Man-Opossum). He played the guitar in Marcus' and Horatio's band. His rival, Thark, played with Poque. Derek theorized that since the master copy of the Summer Semester album caused both races to form, neither could rule the world if it was destroyed. After the battle was over and they were trying to decide who won, Horatio intentionally broke the master copy CD, destroying both Jessse and Thark. Thus, in ending the plot line of the episode, which began with the formation of the Mega64 band by Horatio and Marcus, Summer Semester has reached its conclusion.
He was portrayed by Garrett Hunter.